I had my second lot of Carboplatin, and first of Taxol and Avastin last Wednesday. Seem to have cracked the constipation/diarrhea balance, this time, but have been badly affected by pains in feet and legs. I'm finding it difficult to sleep because of it. Otherwise, apart form being tired all seems fine. I know exercise is important, but I can't work out if it exacerbates the muscle and joint pain or not. Any advice?