Just finished 2nd line Gem/Carbo and avastin. Consultant very pleased with my response to it but I'm very disappointed it's not all gone and now have to live with it knowing it's only a matter of time. Kids are 23 and 19 - I so want to see my youngest graduate but that's 2 years away. Have chosen not to tell family and friends at the moment but finding it very hard to stay positive and not think about how bad it is going to get. How do we live with this every day ladies and why are we the unlucky ones??