thoughts, suggestions, experiences - prolia followed by forteo, endo said

[MayGodBlessYou]

he is a good endo, very bookish and conservative, clever specialist,

ordered (another) scan - m.r.i - as possible fracture higher up than first x-ray taken.

he reckons after 6 years prolia, do forteo no longer than eighteen months, can review at (did he say 6 months?) /a year, then prolia + calcium + vit D.

has anyone had prolia followed by forteo, please.

i need the suggestions,

i acknowledge i've mixed up some things about the whole prolia treatment, so - i have no idea about forteo.

he didn't did mention fosamax but went on to forteo.

i wonder if part of the reasoning is because a fracture qualifies a patient for health dept subsidy ?

he said it's new, but i'm reading it's been approved since 1987?

is it good to do the switch to forteo?

or, stay on prolia?

i don't know why he didn't strongly recommend, but instead gave the choice. and i don't know what's best for Mum.

thank you!

[MayGodBlessYou]

i now see other topics on the same, but chat is welcome again, thanks

[MayGodBlessYou]

best administered during day, or at night?

[MayGodBlessYou in reply to MayGodBlessYou]

i read that taking forteo in the morning may be better

[MayGodBlessYou]

maybe 6 months ago there had been mention by the endo about changing to bisphosphonate. and now he's recommending forteo.

is that because forteo's better than fosamax and prolia, in the event of possible existing fracture? also, what can be done to help the vertebra heal? endo said it may improve. drs (can) only treat the pain;

i feel treatment should resume soon as possible, as it's over two weeks since a prolia shot was due;

even though it's said that 4 week between shots is acceptable, everyone's different; a possible crush fracture is - urgent.

the Lord has helped things move with relative ease;

a cancellation brought the endo apptt forward a day; the imaging receptionist put Mum in an apptt for a day later, after first saying it'd be 10 days away; and then another week till endo follow up.

[Tlflom in reply to MayGodBlessYou]

Cold laser treatments help with pain and speeds healing. This is my 1st choice. I also have had good luck with therapeutic ultrasound in healing. Over the counter are homeopathic meds for bone healing work well too. I do it all, lol! My surgeons and physical therapist are always shocked with my speedy healing. I have had several foot surgeries and broken ribs. Good luck!

[MayGodBlessYou in reply to Tlflom]

thanks so much !

[Raleigh59]

I don’t know bc I am not a doctor but one person on here said forteo and Tymlos are the only choices to heal and strengthen your bones back to where they should be which is hard on the exterior of the bones and softer in the interior of the bones. as opposed to all other choices that may create fake brittle bones.

[Tlflom in reply to Raleigh59]

I think, as drugs go, these are better than some. The natural is better but takes more determination without the side effects of drugs.

[dcdream]

I personally would not rely on comments and other people's experience, as each body is unique and has different issues that impact which meds to utilize, which vitamins, etc are useful and at what level on can exercise, etc. I find the comments here useful because they often have links to research, etc. But I find that what appears to work on some, won't work for others, etc. Seems you are doing the best you can with working with her doctors and seeing what is best at her age. Good luck.

[uncountable3]

Conventional wisdom is that Prolio can only be followed a bisphosphonate. Resorption rebounds strongly after coming off of Prolia. A bisphosphonate knocks out the surge of osteoclasts so you don't loose bone. Forteo won't do that. You will experience the full rebound and Forteo will actually increases osteoclast activity beyond that. You have to hope osteoblast activity is increased enough to overcome the bone being lost. Sounds risky but I'm not a doctor, nor do I know the specifics of your condition.

[MayGodBlessYou in reply to uncountable3]

if you have any links to papers or anything that describes forteo having no action on osteoblast activity after prolia, thanks if you can add them here, please.

in my reading, there is little commentary about it.

i think what happens is that, in a study, if there are bad results some aspect, they just don't put it in the report, they just omit!, and word the conclusions in a way that exclude the failures

[MayGodBlessYou]

thank you, all, as much as i was keen for doc to advise about Mum having a rest from prolia,

Mum doesn't want to deal with daily injections,

and is relatively happy with prolia, given the choice,

and so, i relatively agree with it too.

she had a bit of improvement from back pain yesterday,

i'm encouraging her to rest,

have set up a slanted back rest on the couch

[Raleigh59 in reply to MayGodBlessYou]

my 86 year old lady friend likes Prolia and her friends like it too . She had one friend I think who had cancer who did not do well with Prolia.

[MayGodBlessYou]

recently i found out an elderly family member had been on it 8 years with success

[MayGodBlessYou]

what i notice in the marketing of prolia is that there's a graph comparing the main drugs and bone mass, over time,

the prolia has a high plot, the highest plot -

and i ask and comment, is that really a good thing? is higher better? is the highest the best?

because that would explain why rebound is so severe with that drug

[MayGodBlessYou]

my Grandmothers shrunk a lot, but never broke any bones until wrist fracture, which healed

[MayGodBlessYou]

reading the product info sheet for prolia,on the 2nd page it says at 6 months, 53% of participants had no detectable level of prolia in their system - so -

when did that happen? - at, say, 5 months? 4 months? it doesnt say specifically !

so - as much as i don't like this drug, it seems to me that the recommended allowable delay between doses of 4 weeks, would be too long,

show me otherwise, i'd be happy!

[wellness1]

Are you a member of the Bone Health forum of Health Unlocked? Arcadia10 has written a lot about Prolia and the protocol for coming off it. I believe she has corresponded with a professor who is an expert on this. If you search her posts you will find discussions of Prolia from her, as well as related posts.

[MayGodBlessYou]

my late grandmother fell and broke her wrist in her care home, and it healed,

never broke anything else,

i don't think she was on osteoporosis treatment at the time,

so soon after that she was put on bisphosphonate,

and her teeth quality decreased a lot,

not sure if related,

but related was the effect on her skin, her arms went black and i don't think it was worth it.

[MayGodBlessYou]

i now think that it would've been better if endo reviewed prolia use at 5 years, not at 6 years, so, lazy? he now seems to realise it's not helping now, really wants Mum to start forteo. Mum isn't on daily calcium due to some arterial calcification.

so the mechanism of these drugs seems to be that they need material to build from, and it looks to me like the prolia is taking material from her backbone.

i thought that Mum was slouching in her chair, but it's because her back has rounded more, so she is just trying to get comfortable and keep her head upright.

i think that doctors, endo, blood specialist, radiographers, dentists, all know what is happening, or making the connections;

they don't say anything cause the situation is unspeakably bad,

they're helpless to change anything or say anything, but at least they KNOW.

[MayGodBlessYou]

in the last year or 2, it seems that dr endo mentioned to Mum about taking bisphosphonates. maybe i wish that that got started.

when Mum asked him about it a couple of weeks ago,

he said the action is the same as prolia,

that's what i think i heard.

and maybe the need to build up bone is more urgent.

i'm concerned that stacking medicines is harsh on the body,

and that prolia shouldn't be stopped

take care everyone