Thanks to all who replied to my question yesterday when I asked if I should try to fight a sore throat myself. I took your advice and called the surgery at the obligatory 8am to make an appointment. They could fit me in just after 10 so I took the dogs..or should that be the dogs took me... on their usual 40 min walk around the village and went to see the Dr who confirmed it is tonsilitis and gave me a prescription for antibiotics. I asked if I should still take my mtx on Friday as usual and she said she thought so and didn't see any reason why not. Straight after the Dr's I raced up to the local hospital for my OT appointment where I was fitted for a resting splint for my left hand, the right was done a couple of weeks ago. Although I don't need it at the moment she thought it would help to be prepared. A trip around Asda followed to buy the weekly groceries and then off to the chemist to pick up my prescription...the chemist was closed so back in the car and off to another chemist which was thankfully open. Well the pharmacist came out and confirmed I take mtx and said the anti biotic I'd been prescribed increased toxicity of mtx and twice weekly blood tests were indicated!! I'm on monthly. She also thought a different antibiotic may be safer but would need to speak to my Dr. Long story short she is going to call my Dr this afternoon and confirm which antibiotic I should have and have it delivered at tea time (yay). Well shopping is away, it's 2pm and just sat down. I doubt I'm alone in feeling sick of the sight of hospitals, GP surgeries and pharmacies. This new life really does take some getting used to. I feel just a tad fed up, knackered and would like to take to my bed and sulk but for now I'll have a little relax before tackling the ironing pile! I really admire those of you who work as I don't know how you manage. I hope you are all well and any advice on antibiotics with mtx would be greatly received.