Sulfasalazine

[Alice70]

My rheaumatolgist changed my sulfasalazine to sulfasalazine En-tabs because I thought it was them that were upsetting my stomache I have been on E-tabs for a month now I'm feeling sick and loads of gas ,what I'm wondering is can the En tabs still upset the stomache or not maybe it wasn't them in the beginning,she also changed my prednisalone to gastro resistant,feed back would be appreciated I'm also taking 30mgs of lansoprazole and I know these bloat me

[rmros]

I can't remember the reasons but thinking back to the time I was on sulfasalazine and the pharmacist gave me the wrong type once, iirc the enteric-coated tablets are the only ones licensed for RA. The other ones are for crohn's disease and other inflammatory bowel disease. So they would have been prescribed off-label to begin with.

If your bowel problems go on you'll need to have it investigated as it might not be related to the medication at all. Or try some over-the-counter IBS treatments to see if they help.

The one benefit I had on sulfasalazine was it settled my IBS, so I had the opposite problem.

[Alice70 in reply to rmros]

Spoken to rhraumy nurse she told me to drop two one 500mg a day,I was about to try buscopan for IBS ill wait now to see if better onthe one tab thank you

[whitedog]

I had upset guts for a while when I first changed to Sulfasalazine but since then I've never felt nausea with it and I stopped the Lansoprazole I'd needed with Methotrexate as I wasn't getting such bad acid reflux.

The GP was happy about that, even though I'd been on it and had it on repeat for 10 years. And then I learned from the local pharmacist that Lansoprazole is designed to stop acid reflux happening but once you have those symptoms, Gaviscon is better as it puts a lid on it. No one ever told me that before.

Anyway, at one point, I started buying lactose free milk as I seemed to be a bit windy but I'd never thought it might be down to Sulfasalazine. It did help, and I still buy it, but do also drink ordinary semi skimmed. Worth a try?

[Alice70 in reply to whitedog]

Spoken to rheaumy nurse she told me to drop down to one tab twice a day instead of two thank you , I find lansoprazole makes my stomach makes to much gas