Anyone with experience of Yuflyma?

[virtualreality]

Hello all,

I'm being prescribed Yuflyma which I understand is a fairly new adalimumab biosimilar. Apparently it's a high concentration injection so less painful to inject and (crucially) cheaper than alternatives.

Although I know we're all different, I'd really appreciate hearing about other people's experiences of this medication, and any measures you've been advised to take in relation to reduced immune function (like avoiding raw milk, unpasteurised foods, anything else..). It's my first biologic. The info shared by the rheumatology team has been pretty minimal...

Also, deliveries are going to by HealthNet Homecare not Sciensus, which sounds like it could be a good thing. I need deliveries to be as reliable as possible because it'll be quite hard to organise my job around them. Anyone else been switched to this service? Are they any better?

Hoping this'll be the change that gets me back to a full-time life, fingers crossed. Thanks in advance for any experience or advice you can share!

[Lolabridge]

Healthnet Homecare have been very good and reliable for me. They always deliver within the two-hour window notified.

Good luck with Adalimumab, which is one of the antiTNF biologics. Many people find those work well for them but sadly not me.

Hope your experience will be good!

[virtualreality in reply to Lolabridge]

Thanks Lolabridge , very encouraging to hear that about Healthnet homecare. Trying a new medication is such a lottery, isn't it. Hoping I'll be lucky with this one.

[KittyJ]

another thumbs up for Healthnet Homecare from me, easy to book a slot, always on time and drivers are lovely.

[virtualreality in reply to KittyJ]

Oh that's brilliant to hear, thank you!

[Tuppy66]

Hi,

I would think any delivery company would be better than Sciensus the really are terrible and one hand doesn’t know what the other hand is doing so to speak.

As for the biologic, when the original patent ran out for Humira they put me on a similar biologic supposedly the exact same drug however I lost 18 months of my life, so eventually they got permission and funding to put me back on the original Humira which I took in conjunction with Methotrexate. I appreciate you have nothing to compare with but it appears that carrier liquid in the bio similar medication can cause problems in some people as I found out. Just make notes on how you are feeling. I found I got my life back when everything settled down and I had been on the combination of Humira and Methotrexate for about 3 to 6 months. Now sadly I’m in freefall as I have had my Methotrexate taken away as I have developed a fatal bacterial infection in my lungs and respiratory tract which they are finding it hard to treat. Like I say that’s a whole other story.

As for what you can and cannot eat drink etc do stay away from unpasteurised foods and raw fish, sushi etc. Alcohol in moderation and for the most part just use your common sense, I miss blue steaks so once in a while I will take mine rare but at a restaurant I use frequently. Good luck to you and I hope you get your life back.

Merry Christmas and a Happy and Healthy New Year

[virtualreality in reply to Tuppy66]

Thanks for sharing your experience Tuppy, I appreciate it. Sad to hear that the food restrictions are actually to be followed, though! (I know the advice varies from team to team). Very glad you got back to Humira - I've heard of others being swapped to a biosimilar and finding it less effective. Hopefully I'll be lucky with this one. And I hope there's a treatment round the corner for that bacterial infection for you. Wishing a merry festive season back to you, and a good 2024!

[pammi2]

I staerted yuflyma in June and guess what IT DONT work they now want me to go onto either Rituxumab or filgotinib, any advise anyone using it, dont like side effects

[Hannah100 in reply to pammi2]

Hi Pammi2,I was on Rituximab infusions for 4 years having had Benepali, failed after 8 weeks, Toxciluzimab for 18 months which didn't work, then Baricitinib for a year, which was like swallowing smarties. I don't like taking meds at the best of times and was so ill on methotrexate, lost 10lbs in 3 weeks, great for slimming. Anyway, background to Rituximab, it worked really well for 3 years, not one day off sick from work, did have odd flares, but had 20mg of prednisolone that settled them down straight away. Definitely was good. As a hint, I had to take 20mg of Prednisolone a week before first infusion as my hands and wrists used to swell up, but again that sorted me out no other side effects. Go for and and good luck, don't believe everything you read.

[pammi2 in reply to Hannah100]

HI thanks, I didnt read, my Rhuemy told me side effects were you get more viral infections?

i mean immune system is weak already thats why you have RA and top of that to make it weaker but also Methotrexate makes it weaker