When u started mtx 4 weeks ago the side effects weren't too bad. Slight stomach cramp and a little nausea. 2nd week the same. I thought this isn't so bad if it's gonna help I can put up with this! 3rd week cramping and stomach pain for approx 3 days. This week my 4th dose is horrendous. Stomach cramps with I have to take meds for hot water bottles etc. constant nausea and diarrhoea I am so fed up. Has anyone else who can't tolerate mtx found that the side effects worsen as the weeks go on please? Should I persevere? on holiday next week and not going to take my dose. Will ring rheumy nurse Monday to confirm it's ok.
Thanks in advance for reading