I saw my Rheumy yesterday. She is now changing to Orencia. Unlike Humira, she wants to switch to infusions. I have read about infusion reactions. It does frighten me a little. Have any of you experienced problems with this drug? I ordered genetic testing in hopes of avoiding drug reactions. I do not have results as yet. My shop was to be sold effective today. The buyer is apparently backing out.I just spent 6000 restocking the freezers. I am at a point were I hope I do have a heart attack so I do not half to deal with this anymore. What is wrong with people.