My husband has had awful problems with various DMARDS and came off Suphasalazine in September after bad side effects. Since then he has had problems with increasing CRP levels (now at 50), low iron and b12. He has also started itching all over his body - this is keeping him awake at night and he large sores where he has scratched. The rheumy nurse says itching nothing to do with RA but gave him an appointment for a review with specialist at end of January. He has been visiting his GP weekly, tried various creams and antihistamines all of which have had no impact. The GP has now said its systematic not topical and no cream will stop the itch. They've tested him for his liver and he's had an endoscopy as they thought the low iron could be a result of a bleed in his stomach - thank goodness all clear. The GP yesterday has now told him to stop Naproxen, up hi so cocodemol to max and wait for RA appointment at end of January. We get the feeling GP is out of his depth. Anyone else had similar issues?