So husband has started itching again and once again the rhuemy and dermatologist have no idea what causes it. He has had episodes of itching and rash that seems to start from the inside of his body. It develops into open sores that spread from his legs across the rest of his body. It started when he stopped taking the methotrexate, which he's been on since 2009. The only thing that stops it is going back the methotrexate. He was put on low dose last year as his RA in remission but he needs a maintenance dose to stop the itching. Now he's started itching again and it seems the low dose is not enough to keep it at bay. His skin is not dry, it's not eczema, it's not psoriasis, it's not allergy related and I've not changed washing powered or soap but when it takes hold its bad enough to curtail his life. ra is bad enough without this. Anyone else experienced this or know what it is?