A year ago, when my RA with Polymyalgia began, I was started on Prednisilone - first fortnightly injections, then tapering tablets. I became euphoric, and managed to achieve a huge amount in a manic way! I can't quite remember what dose I got down to before the euphoria changed to terrible agitated depression; I was in shreds and felt in real danger. Clearly, I had been brought down too rapidly. The dose was immediately increased and I tapered much more slowly until I got down to 3mg. Because I was in great pain again, the MTX/Sulfa'/hydroxy' weren't working as well as hoped, and the process of getting onto Anti TNF seemed so lengthy,
I was persuaded to increase Pred' again, against my better judgement. No euphoria this time, just extreme anxiety and irrational anger. I have gradually got down to 12.5 mg and sense that this is where it starts to get difficult, I am getting such conflicting professional advice about how to get right down to zero, that I would be really grateful for feedback from those of you who have been there. I realise that we are all different, but anecdotal evidence is still the most helpful.