After a long battle and many setbacks i started on Cimzia yesterday.Healthcare at home sent a nurse to show me how to inject but used to inject Methatrexate before getting really bad mouth ulcers so was fine with it. My hands have been getting so swollen that a ligament became detached so had to have that operated on by my hand surgeon who said to me "we are going to be seeing quite a bit of each other" slightly worrying but he is a top bloke. Again when you have such active disease its about a trade off between a drug that can help you and possible nasty side effects no matter how good your Dr's are the buck stops with us and our main carers who take a huge amount of pressure when we are unwell, in my case my wife is not just in that role but acts as a go between for Consultants and their PA's. i have tried very hard to take control of this but am concious that i have failed on 3 more traditional drugs and the effects of that have left me hospitalised for long periods. Here's to this drug working and getting some of my life back and having time with my Grandson, good luck to those of you who have similar difficult decisions to make, will update as time moves forward.