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21 years old with RA diagnosed when 5

So I was diagnosed with I was 5 with RA and I was different medications for it. the last one I was on was methotrexate until I was 18 because legally I had to be treated for it, since then I haven't been taking meds for it. but this may be a silly question, I am just curious but every time I drink even if I drink a few fruity drinks then go to bed sober I wake up with a hangover, or if I get drunk and drink lots of water still waking up with a hangover. do you think the methotrexate had long term affects on my liver or just my metabolism is just slow?

6 Replies

Sorry dear..I don't know .....I hope someone else can answer you honey...I would think it stays in your system a while but I have no idea how long...I've been on it about eight years now and keep having to have rests due to side effects going bananas. Take care dear. Maryx


There's a cure....... Don't drink so much lol ha ha.

Sorry I don't know the answer but I wish I was 21 again xxxxx


I don't know either - probably best to ask your rheumatologist. Hope you get some answers soon.

All the best, Fran.


Do talk to your GP or rheumy team, but also do remember that some people just don't have a head for alcohol and just can't really tolerate it. Alcohol is actually poisonous to the body, and in some people they just can't cope with that - a bit mean since otherwise it's fun. My sister (now age 60) has never been able to manage more than one glass. So it's quite possible that you've always been like that and it's nothing to do with the drugs you've been on. After all, when you were on MTX I guess you had the normal monitoring like the rest of us, so if it had started to affect your liver you would have been taken off it. And livers are quite remarkable in their ability to repair minor damage.


Hello it could just be the alcohol may just check with the gp. Some people cannot tolerate much alcohol anyway. Take care x


the only way you would know if it had affected your liver would be to get the GP to run some liver function tests and perhaps an ultrasound.

Bear in mind though, that long term untreated inflammation can also in some circumstances lead to liver, kidney and a host of other problems. Now that you are "adult", it might be worthwhile having a really adult conversation with your rheumatologist (get referred again if you aren't under one right now) about long term prognosis, and what your treatment options really are. Treatment options can be slightly different for adults than children.


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