Hi. Just after anyone's experience with simponi. I have been on this for 6 months now and have had one infection after another from flu, tonsillitis and even shingles. I was on rituximab previously and felt I did well on it however the PCT would not continue it. In the eyes of them and NICE I did not show a good enough response. After a battle involving my MP I started simponi. I am so fed up with how I feel on it generally. Have rheummy app on Friday and want to stop simponi. I know I have reached the end of anti tnf's as have tried lots. I feel more depressed by the associated illnesses then I did with the RA.