I have talked to my Nephrologist about medication for ckd 3b, and she discussed Jardian and Farxiga
She told me that Farxiga causes severe dehydration, which forces you to drink up to 3 litres of water per day, which is TOO much
Does anyone know ANY other medications that do NOT cause dehydration?
Thank you
i looked up a couple just out of curiosity and at least to me the side effects outweigh the use of the meds.its just me of course but the ones ive seen all cause dehydration
Hi, Jeff. I have been on Farxiga for over a year now. I drink around 50-75 oz of water along with one 20-30 oz unsweetened iced coffee per day. I can tell immediately if I am getting dehydrated, because my mouth and lips become very dry, and I get a headache. If that happens, then I increase the amount. I don’t get lower foot and leg cramps, if I drink the aforementioned amount. I don’t believe I’ve ever had to drink 3 liters per day. I know that if the legs and feet are swelling, the body is retaining fluids, and too much water can be harmful. I’m not sure if Farxiga has been truly effective for me, but I have maintained my gfr, etc., for a year now. It is also supposed to be good for heart disease. I hope I’ve given you some insight. Maybe you can re-address the issue with your doctor.
I would be concerned about the Jardiance. do you know what your eGFR level was? per the FDA label patients who have an eGFR I believe below 46 or 45 shouldnt start Jardiance or if they were put on it before their eGFR levels dropped but are consistently below 45, they're not suppose to be on it I dont think. but thats what I thought the FDA label said
i believe farxiga is better but worried about dehydration issues
Drinking more water is definitely recommended. GFR levels can fluctuate if dehydrated at time of blood draw. I try to get plenty of hydration in the day before I have lab work done. I don’t believe I have had a problem with it while taking Farxiga.
She is misinformed…EMPA-Kidney studies and 4/5 others since okay Hardianxe specifically down to eGFR. Additionally in non-T2D CKD stage 4 patients it’s proved for many safer than ARB’s /ACE unfortunately many as I related my specialist story in another post don’t follow the advancements in gar have come recently…in the US it’s a reimbursement driven cycle and those dialysis centers attached to the specialist office pull in huge $…the studies are out there the UK has been a leader in the push to develop something besides “okay wait till they fail and THEN I’ll be able to help mentality…link to EMPA-kidney study:
The primary results from EMPA-Kidney were published online in the New England Journal of Medicine on November 4, and were presented here at Kidney Week 2022, as previously reported. In terms of the trial's primary efficacy outcome, treatment with empagliflozin (Jardiance) for a median of 2.0 years in patients with CKD significantly reduced a composite outcome of progression of CKD or death from cardiovascular causes by 28% compared with placebo.
Link:medscape.com/viewarticle/98...
the nephrologist in this article Cole even states:
"Importantly, EMPA-Kidney broadens the population at risk," especially people with CKD without diabetes, without proteinuria, and those with an estimated glomerular filtration rate (eGFR) of less than 30 mL/min/1.73m2, commented Janani Rangaswami, MD, professor and nephrologist at George Washington University School of Medicine and Health Sciences in Washington, DC. "This is a win for patients with stage 4 CKD," she declared, reversing the "nihilism for stage 4" that's manifested in the past as low representation of these patients in trials of treatment”
Show this to her…though it’s been my experience that just makes them mad and they think you think you know more then their precious $100,000 education and all their hours and of residency…if they puce lived with the disease 29 years as I and others have and FINALLY something come that offers real hope and a docs PRIDE stand in the way of a potential better quality of life for a significant period of time is a real slap in the face…I don’t have a problem telling them that either…which is probably why I don’t have the script either…lol!
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