CKD 3b Farxiga Poll

[jeffmensch]

I would like to know people's ratings for Farxiga from 1-10, for

HELPING IMPRIVE eGFR 1-10 1 is NO increase, 10 is Increase to OVER 60

SIDE EFFECTS 1-10 - 1 is NO side effects, 10 is TOO MANY

[taiglum]

GFR - 1 Side Effects - 1. Been on Farxiga almost 2 years.

[jeffmensch in reply to taiglum]

has it raised your eGfr being on Farxiga?

[taiglum in reply to jeffmensch]

No not at all. I also have not lost any weight on it. Seems like a bit of a useless pill.

[jodaer in reply to taiglum]

I think the better question would be did your eGFR go down and if so by how much?

[jeffmensch in reply to jodaer]

eGFR should improve with medication, not decrease; Anything under 60 is not good; Mine is 40, and want to get back to 60 range, to feel safe

[jodaer in reply to jeffmensch]

I disagree, not all medication improves a condition. It might keep it from getting worse and maybe hide some of the symptoms, but rarely does it actually make it heal.

[jeffmensch in reply to jodaer]

only point of certain medication is to IMPROVE, if not improving, or keeping stable, NO need for medication

[bumblebee_tuna in reply to jeffmensch]

Farxiga doesn't improve eGFR - it's renal-protective and has been proven so in quite a few randomized trials. It doesn't raise your eGFR it slows down the progression of the disease.

[jeffmensch in reply to bumblebee_tuna]

I have read other comments about people who have improved eGFR from Farxiga,

[bumblebee_tuna in reply to jeffmensch]

Probably in an indirect way by improving the underlining disease (Diabetes).

[CuriousCKD in reply to jeffmensch]

An increased GFR could be due to a good ckd-friendly diet and staying hydrated. My doctor told me that stress and dehydration cause it to fluctuate, from one test to the next. Also managing sugar and blood pressure levels.

[CuriousCKD in reply to jeffmensch]

I would love my GFR to be at 60. Mine has been hovering around 23-26 for over a year.🤔

[jeffmensch]

sorry to hear, too bad your egfr did not increase

[pghgal]

My doctor told me Farxiga would make egfr worse

[jeffmensch in reply to pghgal]

wow-research and this group shows improvement - i would ask a 2nd opinion

[pghgal in reply to jeffmensch]

My nephrologist said it helps some people but only if you are diabetic and I'm not diabetic and it would lower mine.

[jeffmensch in reply to pghgal]

im not diabetic either but I have read it can help with people who are not

[jeffmensch in reply to pghgal]

“Among patients with stage 4 CKD and albuminuria, with and without type 2 diabetes, the effects of dapagliflozin on reducing the risks of major kidney and cardiovascular events and attenuating progressive loss of eGFR are consistent with those observed in the trial overall, with no evidence of increased risks. Dapagliflozin should be considered part of the therapeutic armamentarium for patients with stage 4 CKD and albuminuria,” wrote investigators.

[bumblebee_tuna in reply to pghgal]

There is usually an initial drop in eGFR when you start taking it, but I wouldn't say it is making your CKD "worse". The drugs has been proven to slow down the progression of CKD.

[jeffmensch in reply to bumblebee_tuna]

I do NOT understand: "but I would say it is making your CKD "worse"

[bumblebee_tuna in reply to jeffmensch]

sorry I meant "wouldn't"

[taiglum]

Well I am diabetic and my Gfr in the past two years since starting Forxiga just fluctuates between 14-18. I also have gained around 45 lbs in the past two years. Also had a heart attack at Easter time. Really don't know why my Nephrologist is keeping me on this pill. It must help some folks I guess.

[jeffmensch in reply to taiglum]

my kidney doctor told me that farixga creates a lot of dehydration issues

[Bassetmommer NKF Ambassador]

Farxiga is a diabetic drug. By helping to lower someone's A1c, or sugar levels, helps with kidney function. They say it is renal protective, which means only it does not harm the kidneys. Does not mean it will improve a GFR. It may as a result of better glucose maintenance. As yes, all drugs can have the potential to harm the kidneys..... look at ibuprofen.

[jeffmensch in reply to Bassetmommer]

kidney doctor tells me farxiga also helps ckd, if u dont have diabetes

[BlueLe]

I have been on it since mid May. Initial blood test after 2 weeks showed drop in eGFR but improvement in Protein Urea. Nephrologist says drop in eGFR is temporary. Time will tell. I am not seeing any unusual increase in thirst or dehydration. Though I am at my daughter’s place and we eat dinner earlier there so water intake is lower in the evening and I go to urinate about 3 times a night and that flow is lesser, day time it is fine. Will see how things go back when I am at home.