PBA Pseudobulbar Affect: One of the lesser... - My MSAA Community

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PBA Pseudobulbar Affect

Jesmcd2 profile image
Jesmcd2CommunityAmbassador
8 Replies

One of the lesser known symtoms of MS is PBA (no l dont have have this)

PBA also known as Pseudobulbar Affect... It involves uncontrolled or inappriate episodes of laughing or crying. These emotional responses don’t match the intensity of your inner feelings. PBA results from certain underlying neurological conditions. It is manageable with medication.

Although episodes of laughing or crying may seem appropriate for the triggering event (such as seeing or hearing something funny or sad), they tend to be more difficult to restrain. They can also be more intense and last longer than you would ordinarily expect. It is a Neurological condition!

PBA may be called several other names, including:

Emotional lability.

Pathological laughing and crying.

Involuntary emotional expression disorder.

Compulsive laughing or weeping.

Emotional incontinence.

PBA can have a substantial impact on your life and the lives of your family members and caregivers. It can cause embarrassment and anxiety, leading to withdrawal and social isolation.

(Please dont let it!)

What are the symptoms of pseudobulbar affect (PBA)?

It’s important to know the difference between mood and affect when understanding PBA. Mood is your subjective experience of an emotion. It’s your inner feelings, such as sadness, anger or happiness. Affect is the visible display of emotion that others can see, such as smiling, laughing or crying.

Based on this, the main symptom of pseudobulbar affect is affects — often crying or laughing — that don’t match your mood or the intensity of your mood.

The laughing and/or crying can:

Be unpredictable, sudden and involuntary. Be out of proportion to the trigger. Happen for no apparent reason.

Involuntary outbursts of anger or frustration may also occur.

Since PBA is often associated with underlying neurological conditions, such as a brain injury or ALS, people with PBA will likely have other symptoms that correspond with the underlying condition.

Several neurological conditions can cause this disruption and are associated with PBA, including:

Traumatic brain injury.

Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease.

Multiple sclerosis (MS).

Alzheimer’s disease and other forms of dementia.

Stroke.

Parkinson’s disease.

Brain tumors.

Epilepsy

Wilson’s disease.

How is pseudobulbar affect diagnosed?

Pseudobulbar affect (PBA) can be difficult to diagnose. Healthcare providers often misdiagnose it as a mood disorder — especially depression or bipolar disorder.

Currently, there’s no definitive test to diagnose PBA. Healthcare providers base a diagnosis on a thorough understanding of your:

Symptoms.

Medical history, especially neurological conditions.

Mental health history.

Finding from a physical exam.

How is pseudobulbar affect treated?

There’s no cure for pseudobulbar affect (PBA), but certain medications can help manage it. The goal of treatment is to reduce the frequency and severity of episodes of laughing or crying.

Medications that healthcare providers prescribe for PBA include:

Dextromethorphan/quinidine sulfate (Nuedexta®): The FDA has approved a combination of dextromethorphan (a cough suppressant) and a very low dose of quinidine sulfate (a drug used in the past to treat cardiac arrhythmias) as the first drug specifically developed to treat PBA.

Antidepressants: Tricyclic antidepressants, selective serotonin reuptake inhibitors (SSRIs) and norepinephrine/serotonin reuptake inhibitors may help manage the symptoms of PBA. The doses are typically lower than the doses required to treat depression.

All medications have possible side effects. You’ll work with a provider to determine the best treatment plan for you.

All this info AND MORE can be found here.... my.clevelandclinic.org/heal...

What about you? Do you think you have PBA? Or do you have PBA?

🤗💕🌠

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Jesmcd2
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8 Replies
Kenu profile image
Kenu

Good read 👍🏼😉

Jesmcd2 profile image
Jesmcd2CommunityAmbassador in reply toKenu

Long read! 😞😴🤣🤗💕🌠

falalalala profile image
falalalala

It sounds like a woman I used to work for.

She had MS for a number of years and her reactions often didn't match the situation.

Tazmanian profile image
Tazmanian

I have PBA I take lexapro

BlanketTime1 profile image
BlanketTime1

thx for sharing!🤗

cindyrn68 profile image
cindyrn68

My husband had PBA with his ALS. Nuedexta was very helpful for him!

Fancy59 profile image
Fancy59CommunityAmbassador

Jes, great comprehensive post!

Years ago I had one episode of the disorder and it never happened again. I was camping with a bunch of friends and the boys were throwing a football around and it Landed by my feet so I picked it up and went to throw it. Of course I'm no Tom Brady, so when I tried to throw it, it wobbled like crazy and came up short, then took a bad bounce and hit One of my best friends in the face and broke her glasses.

OMG! I couldn't do that again in a 1000 years if I tried a 1000 times. But it happened Nonetheless and I was horrified. But instead of running over and showing concern I started laughing hard and I couldn't stop. I felt like a complete hyena and I didn't know what was wrong with me and where the laughter was coming from. At that time I was yet to be diagnosed with the MS and I'm sure as Jes pointed out it was a neurological response from my MS. I'm just glad it's never reared its ugly head again. Thanks for the post it was great! Fancy59.

Jesmcd2 profile image
Jesmcd2CommunityAmbassador in reply toFancy59

You laugh at everything! 🤣😂🤣🤗💕🌠

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