I took steroids, once. It was in the summer, it was really hot and I was just having all kinds of issues flaring up. Left side weakness, a limp, tingling, fatigue, muscle spasms. My MS nurse practitioner wasn’t sure that it was an actual exacerbation or caused by the heat, and stress. She thought a course of steroids might help so I gave it a try. I remember having to take a bunch of pills but I think I started out intravenously on a Friday and then had to take the pills over the weekend as the office was closed. This was over ten years ago.
What I remember most about it was that I had the worst depression I’ve ever had in my life and that’s saying something. I even had to take a few days of sick leave from my job. I remember thinking that if I ever wanted to kill myself, prednisone would make it very easy!! And that I would never, ever take it again.
That is my experience. Hope it helps.