My neurologist is back on the pushing me to change from Tysabri to Ocrevus...I still have reservations. Having my total knee replacement 4/22, with last Tysabri infusion 4/17. Dr. wants that to be my last infusion and then have the 6 week washout during recovery from surgery. I am SPPMS and have been for 12 years. The only downside to Tysabri is fatigue crops up 2/3 of the way through the infusion cycle. Dr. is convinced Ocrevus is the way for me to go. Thoughts??
thanks, Vicki
There are lots of people either on it or due to go on Ocrevus but at the end of the day you need to do what you are comfortable with, so you need to discuss it with your doctor and neurologist. I hope everything goes well with your knee operation. Let us know how you get on, Blessings Jimeka 🦋
Has your Dr given you any really good reasons for why he/she thinks you should change? Are you JC Positive? Has Tysabri continued to be effective in managing your MS?
One thing that is really important to keep in mind is that any prosthetic implant in your body has no blood supply and can thus become a "hiding place" for infections. All of the immune suppressing MS drugs create a higher risk of infections, which can be particularly problematic if you have bits of you that have been replaced or repaired with a prosthetic e.g. a knee joint, or a hip replacement etc. I think you need to talk seriously with your neuro and your orthopaedic team about these risks and be as informed as possible before making a decision one way or the other - which needs to be a decision you are comfortable with.
Good morning Vickisue55, I have been on Tysabri for at least 3 years. With great results. I'm spms and have been for years. My doc has talked about Ocrevus, we have decided to stay on my current treatment. Talk with your doc and tell him / her how you feel. I wish you all the luck in the world for your surgery. Bob
My neuro says Ocrevus is the only MS DMT that slows down disability progression. It has no side effects. If you have progressive MS, is Tysabri really good for it? The whole JC virus would have scared me off if I had ever considered it. Of course, I am not a doctor but a patient on Ocrevus.
my ms is not primary progressive, just secondary/chronic progressive. I have remained pretty stable for the last 10 years. Just about decided that I am going to stay on Tysabri for now. Thanks for responding.
I have had 2 doses of ocrevus and so far really happy with it. I had several reactions to tysabri so i am glad ocrevus came out. Good luck to you and your surgery.
What were your reactions?
My reactions were i felt like i had a elephant on my chest. They had to keep stopping it and let the chest pressure get better then try again. Ocrevus is so great . I have had 3 full infusions and no problem. Good luck to you
side effects for me with OCREVUS are hair loss a lot and weight gain. Good luck with whatever you choose.
Ocrevus Talk with Neuro
Ocrevus vs Tysabri/ iv steroids
Ocrevus
