ssdw1958 ... MS patients are not supposed to get any of the live vaccines particularly if you are on any of the immunmodulating DMT's.
Ocrevus specifically kills off your B cells so vaccines are much less effective, if at all, so need to be carefully timed. There is a study underway to test the effectiveness of "killed" vaccines on patients with Ocrevus. clinicaltrials.gov/ct2/show...
Yeah...but with Ocrevus killing off the B cells, no one has a definitive answer about whether or not getting a 'not live' vaccine is going to work to provide immunity. I talked to my neuro about this because I don't understand why its unknown since there are other drugs available with the same B cell mechanism.
That's why I was disappointed that I didn't know this in time to get Shingrix before I started Ocrevus.
I’m on Aibiago and my neuro said to get new vaccine, shingrix as it was not live. Went to pharmacy and was told getting it in January, would be two shots two months apart. He stated info he received it was 91 percent effective verios the old at 51 percent. The pharmacist said he has been telling everyone for the last month to wait for new one. He said insurance only pays for shingles shots once. So I’ll wait till the new one comes in.😉 Ken
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