My friend Pat

[Friendofpat]

Patricia has been diagnosed with MSA in her mid 50s. Until recently she was still able to get around but had to give up driving. Does anyone know if there are any studies of the effects of the LDN drug on MSA patients? Apparently it is more effective when it is taken with vitamin D supplements.

[Yanno]

Hello Pat's friend,

My wife Jackie has MSA-C and we were recommended LDN some time ago. We've been unable to find any real evidence of LDN being used with Multiple System Atrophy. Jackie has used the drug for sometime (now on full dosage) and perseveres despite probably not seeing any huge benefit. Her real motivation now is to try and create some evidence that LDN does or doesn't work.

I responded to a post on the PSP forum and you will see my response here. healthunlocked.com/psp/post...

Should you come across any evidence of the use of LDN with Multiple System Atrophy then we would be very interested to hear. Incidentally many people have referred to so called evidence but sadly on investigation it appears to have been used for MS (Multiple Sclerosis) not MSA.

Not good news but hopefully helpful.

Take care, Ian

[Friendofpat in reply to Yanno]

LDN seems to work best with autoimmune conditions like MS. MSA is not an autoimmune condition so evidence could be be more difficult to quantify.

[sjg15 in reply to Yanno]

I'm not sure what LDN is, my mum has atypical parkinsonism/ MSA diagnosed a year ago and has responded well to Madopar which is a Levodopa mixture, the neurology nurse tells me some patients with MSA respond well to Madopar even though it's more usually seen as a parkinsons drug

[Friendofpat in reply to sjg15]

Low Dosage Naltrexone (slow release) only available on private prescription at present (UK)