Food and supplement relation

[kamiilos]

Hi,

Wonder what's your opinion about anticoagulant supplements such as fish oils, Curcumin versus foods reach in Vitamin K like most of green veggies.

Could there be no contraindications while consuming both as it kind of evens up ?

I came across many comments not to have fish oil, or drink celery juice, eat broccoli with PV but I personally consume both as it makes me feel much better.

But deep down I wonder at times if there may be a consequence.

Kamil

[Spanelmad]

I have been told to watch my intake of kale because of the vit k and clotting risk ( I've had bilateral PE).

[ainslie]

maybe one to check with your Haem, personally I eat broccoli or cabbage 3 times a day, take ciircumin, K2, sometimes eat fish every day for 6 weeks on holiday, I suspect the benefits greatly outweigh the risks if there are any risks, I’ve done above for 14 years with PV. I did ask my expert Haem if any problem doubling circumin dose to help mild arthritis, he dismissed any blood thinning concerns I had re circumin. That’s just my experience and of course may not apply to everyone.

[kamiilos in reply to ainslie]

Thank you for the comment, as mentioned additional supplements and food reach in nutrients help me stay fit and active.I take vit D3 but was told without K2 it collects calcium in veins, thus I consider trying d3k2.

[ainslie in reply to kamiilos]

I take both but at different times, I read it’s better not together but not sure how important that is

[Blucloud in reply to kamiilos]

Calcium in veins? That’s disturbing. I take 2000IU D3 every day and I don’t take K2.

[hunter5582]

The one warning I have consistently seen is that fish oil can potentiate aspirin, raising risk of hemorrhage. I expect like most things people with MPNs encounter, we are each different in how we respond. Curcumin might have a mild potentiation of aspirin for some, but having combined curcumin with aspirin for many years, I have not had a problem with this. Note that I also take a Proresolving Mediator that is a fish oil derivative. I am taking both of these supplements under consultation with an Integrative Medicine doctor and with the knowledge of my MPN care team.

Regarding diet, I eat whatever veggies my heart desires. Very broadly speaking, one would have to consume massive quantities of almost any vegetable before the nutrients in them would cause a problem. There are exceptions, like grapefruit juice with some medications. Best to check with a pharmacist about drug-food interactions. Note that all doctors are not equally knowledgeable about nutrition and specific diseases. Certain specialties (e.g., integrative and Functional medicine) are more knowledgeable than most. The role of diet in managing MPNs is an area of active research. If you are seeing a MPN Specialist, your provider may be up to date on this issue.

While these resources are not a substitute for consulting with a knowledgeable medical professional, they can be helpful.

Supplent-drug interactions reference.medscape.com/drug...

Info re. Herbs mskcc.org/cancer-care/diagn...

Info re. supplements rxlist.com/supplements/arti...

Wishing you all the best.

[kamiilos in reply to hunter5582]

Thank you for sharing Hunter, very informative links and all in one pill.

I had appointment with an MPN specialist regarding treatment and few Naturopaths a while back when diagnosed with PV but since then I just follow their recommendations and don't book additional appointments. This is because I feel okay and have no major side effects.

They also did not mutually discussed my case but gave me separate recommendations which were similar.

Not sure if I should continually make appointments with MPN specialist, as while on Pegasys 45 mcg fortnightly my CBC is in range. Even my liver enzymes stabilised after I learnt from you about Milk Thistle which I thank you for.

Wishing you well.

[hunter5582 in reply to kamiilos]

I maintain an ongoing relationship with my MPN Specialist, seeing her once/year. I can see her more often if needed or contact her through the patient portal as needed. I also have a local hematologist who handles the ongoing care. They consult as needed.

I also consult PRN with my Integrative Medicine doc. I have not asked her to consult with the hematology team as I can handle that part of the case managment myself.

Wishing you all the best.