ET and anaemia

[lynnieb]

I have ET with my platelets running at around 1200. I take aspirin, (another condition makes medication tricky). My last GP appt I had a blood test and I'm anaemic. This is the first time this has happened so its a bit concerning. Having them repeated so fingers crossed it will have been a blip

[hunter5582]

Best to double check the iron panel and then review it with your MPN care team . Anemia in the context of a MPN is something that needs a proper evaluation by a doctor with MPN expertise.

Please do let us know how you get on.

[lynnieb in reply to hunter5582]

Managed (with difficulty) to get a GP appt next week. Will also phone my haem team. Will let you know...

[hunter5582 in reply to lynnieb]

Do be sure to check in with your MPN care team before deciding on a course of action. It is important to do a full iron panel as well as a repeat CBC to look at the erythrocytes to properly interpret the results and the appropriate course of treatment. It may also require a Vit B panel. There are different causes of anemia (deficiency in RBC/HGB), including iron deficiency and Vit B deficiency. It is also worth noting that iron deficiency can cause reactive thrombocytosis. Definitely something that needs attention.

Full iron panel

• Serum iron. This test measures the amount of iron in your blood.

• Serum ferritin. This test measures how much iron is stored in your body. When your iron level is low, your body will pull iron out of “storage” to use.

• Total iron-binding capacity (TIBC). This test tells how much transferrin (a protein) is free to carry iron through your blood. If your TIBC level is high, it means more transferrin is free because you have low iron.

• Unsaturated iron-binding capacity (UIBC). This test measures how much transferrin isn’t attached to iron.

• Transferrin saturation. This test measures the percentage of transferrin that is attached to iron.

webmd.com/a-to-z-guides/iro...

Reference Ranges. Note that may vary by lab.

Ferritin 15.0 - 200.0 ng/mL

Iron 50.0 - 212.0 mcg/dL

Iron Binding Capacity 250.0 - 425.0 ug/dL

Iron, % saturation 20.0 - 50.0 %

Iron Binding Capacity 250.0 - 425.0 mcg/dL

Iron Binding Capacity (unsaturated) 155.0 - 355.0

[lynnieb in reply to hunter5582]

Thanks for that

[Yarnhabit in reply to hunter5582]

Really interesting, thank you.