Could hibernating bears help with MPNs?

[hunter5582]

Just came across this article in ScienceNews Hibernating bears don’t get blood clots. Now scientists know why.

Heat shock protein 47, or HSP47, is normally found in the cells that make up connective tissues like bone and cartilage. It’s also found in platelets, where HSP47 attaches to collagen, a protein that helps platelets stick together.

Understanding how human bodies specifically regulate HSP47 is important so that potential drugs find the right balance between preventing clots and too much bleeding.

sciencenews.org/article/hib...

While not overtly related to MPNs it is an intriguing thought that there may be another mechanism that could be used to reduce risk of thrombosis. This type of base science research can yield substantial benefits. Perhaps there will someday be an alternative to aspirin, DOACs and NOACs. Could there be a Bearfarin in the future? Inquiring minds want to know.

[Mostew]

Very inspiring. I'd love to take part in bearfarin trial. Thanks for link

[Wewo01]

Thanks for sharing! I would be happy to take Bearfarin, in the future. Cool discovery.

Hopefully, it would not result in our wanting to hibernate every winter! LOL!

[hunter5582 in reply to Wewo01]

That would be a bothersome adverse effect!

[WRLM]

How does someone go about volunteering for a month of bed rest?! Sign me up! 😂

[Iwillwin123]

I cannot appreciate your studied approach to MPN enough.

I closely follow your line of thought and believe it helps me learn to look at MPN in a more academic manner.

[Andrew8]

I'm already like a bear with a sore head, so I' m told.

[Hidden in reply to Andrew8]

😂

[AdaJane007]

That's really interesting. Thanks for the link

[givingITMybest]

I love reading articles like this. Since my E.T. diagnosis, but more specifically since I've engaged in reading MPN materials, posts and articles presented, talks etc. I feel more like a scientist these days! Thank you