I've read that there is a moderate risk of bleeding after using ibuprofen with Jakafi. I'd appreciate hearing reactions from people on Jakafi who have taken ibuprofen and other anti-inflammatory medications. Which anti-inflammatory medications would minimize the risk of such interactions?
Thanks, Steve
All I was told was not to take ibuprofen only paracetamol for pain relief of joints ect wasn’t told a reason, I should have asked 🙈
Same here; reason that it diminishes affect of your meds or can have adverse reaction. There is a site where you can check interreactions of Jakafi and’s other « drug’s ». I use drugs.com for that.
Thanks for your comments. I'm happy with taking paracetamol for pain, but I would like to know what people on Jakafi do to manage inflammation after a bruise, sprain, or strain.
if paracetamol doesn’t help then I tend to go for an alternative medicine solution depending on the issue (ex chiropractor or physio…), or an analgesic cream recommended by pharmacist.
Thanks for your comments. I'm happy with taking paracetamol for pain, but I would like to know what people on Jakafi do to manage inflammation after a bruise, sprain, or strain.
It seems that people looking for relief from inflammation are taking supplements such as turmeric.
You are correct about the use of supplements like turmeric (curcumin). I have been using it for years to manage osteoarthritis pain and inflammation. It works better than any NSAID I ever took and has had fewer adverse effects. I have never noticed any difference in bleeding issues though that is a caution to be noted.
Hope you find relief ASAP.
Do you take the same dose of turmeric/curcumin every day, or do you increase it for a short period after experiencing an inflammation-inducing incident (e.g. a bruise or sprain)?
I take the same dose every day since I am managing chronic inflammation/pain with osteoarthritis. When i have an acute injury like a sprain or bruise. I usually treat with a topical like Voltaren, Dit Da Jow, or Arnica.
Do you have any thoughts on how to choose among the many available curcumin preparations? Voltaren is diclofenac, so may be contraindicated for those of us on Jakafi. I have no experience with Asian medicine, but Arnica may be a good choice for local relief.
Diclofenac comes as an oral cap and a topical gel. My understanding is that the topical application would be OK with both aspirin and Jakafi. Best to check with your doc or a pharmacist about that.
There are various formulations of curcumin that are bioavailable. I use the formulation recommended by my Integrative Medicine doctor called CurcuWIN. It is available in various brands. The most cost effective is actually available at Walmart. Spring Valley - Turmeric-Curcumin w/CurcuWIN. Be sure to get the exact formulation as there is more than one.
Hope that helps.
Hunter, congratulations on your benign dermatology diagnosis!
I had a televisit yesterday with a CRNP from the Abramson Cancer Center at UPenn. When I asked why I'd been scheduled to speak with a CRNP, she told me that for stable patients, their practice is to alternate visits with MD and CRNP; thus I'll be seeing (virtually) Dr. Luger, my MPN specialist, next May. My questions were quickly forwarded to Dr. Luger, and I got her replies the next day. You might be interested in two of the responses: (1) I asked about allele fraction, and was told that their policy is to consider checking allele fraction after a year of stability on Ruxolitinib; I'll be discussing this with Dr. Luger in May; (2) short-term use of NSAIDs is considered to be safe for those taking Rux. The CRNP also told me that there have been some reports that turmeric can increase platelets, but since mine are now in the normal range, I should continue taking it.
Steve
Thanks for the updates. Glad to hear that you may have the opportunity to recheck your VAF. I do believe is is a good treatment marker. The answer about short-term use of NSAIDs makes sense. The truth is, for managing chronic inflammation, I found that curcumin works better than NSAIDs. I have never heard that curcumin could increase PLTs. Usually hear the opposite, though I think this is not a likely outcome. I would be interested in the data that the NP was citing. Regardless, if it works it is worth it.
I've been on Jakafi for 10 years (it's been very helpful in reducing symptoms). I am in the U.S. and I generally take Tylenol (Acetomiphen?) for sprains. I regularly take a bunch of anit-inflammatory supplements: Turmeric, NAC, Tart Cherry tablets, and Glucosamine and Chondroiten. I try to take these daily. I've had lots of sprains and strains, but I've been easily able to handle them with Tylenol and these supplements (though no one really knows how effective the supplements are, there is some research to support each of them, particularly NAC (not to be confused with NAG, which is for something else entirely).
Hi, I actually take Coumadin on Jackafi and I haven’t had any problems.
Jeanie, isn't Coumadin a blood thinner? I was looking for anti-inflammatory medicines other than ibuprofen and its NSAID relatives, but I'm not sure that there are any, except for steroids.
Hi, yes it is, a very potent one. I thought you were also concerned about bleeding.
WEIGHT GAINS WITH JAKAFI
Question for Jakafi takers.
