68 yo F, with ET , Jak2 mutation, on interferon 45ug every 10 days. I have only been this fatigued once before and I had pneumonia. It definitely started when I went on interferon. I am in hematological remission so don't want to stop.
Do any of you on interferon every 2 weeks find that it made a difference with respect to fatigue symptoms to reduce frequency by this small amount (every 10 days to every 14)?
Second question is regarding being stiff and sore throughout my body all day every day. Have tried NAC, quality curcumin, boron, boswellia, CBD, gabapentin, SPM. All quality supplements at reasonable doses for 2 months or longer with absolutely no difference. The symptom started at night about a year before diagnosis with MPN in 2020 but has steadily increased. My CRP is normal and I have osteoarthritis. My BMI is within range and I eat a fresh mainly local/organic diet.
The only thing that does help is ibuprofen but because of aspirin and possible effect on kidneys (they are fine now) I take it only every once in a while when I really have to do something.
Is there something that treats the inflammation? I really believe the soreness is MPN related as previously I did not experience all over body pain like this. I find my daily activities taking care of house and gardens to be almost impossible, and what is worse, no fun at all.
I have an appointment with my MPN specialist in 2 weeks so this is in preparation as I wish to focus on QoL now my blood is within range.
Thank you.