ASH 2020 | Timing of driver mutations and clonal dynamics in MPNs: a new paradigm for blood cancer development

[socrates_8]

Post by MPN-MATE Admin » Fri Dec 18, 2020 12:27 am

Evening all...

This short You Tube is full of some very interesting theories, and one in particular that I know to be factual in my own case...

... that I have had my MPN for many years before diagnosis.

Fascinating insight to be coming from a Specialist, however, I am sure that many of us might have volunteered these findings long ago, if only someone was prepared to listen...

Nevertheless, an insightful video all the same...

Best wishes all...

Steve

ASH 2020 | Timing of driver mutations and clonal dynamics in MPNs: a new paradigm for blood cancer development

Jyoti Nangalia • 7 Dec 2020

mpn-mate.com/forum/viewtopi...

[mhos61]

Thanks Steve.

Fascinating clip, I’ve read similar recently too.

Wonder if we’re affected in any adverse way in this ‘latent period’.

[Hopetohelp]

Fascinating thanks

[Chaz1]

She's hubby's new consultant, she is amazing!!! So informed, listens & then supports him with what the issues are.

[cabinetmaker]

Thanks Steve, that’s very interesting and goes a long way to confirming what I already suspected.

[Aneliv9]

So if a baby has acquired this mutation will also be detected by blood tests? Or it should first reach some level before it can be detected??

[socrates_8 in reply to Aneliv9]

Hey Aneliv9...

Presumably correct Aneliv9...

Peripheral blood is how we are all usually tested, and apparently, into the future the Next Generation Sequencing (NGS), scans for mutations will be far more commonplace than the prohibitive of costs of today make it for many etc...

Best wishes

Steve

[Ettiel]

Hey Steve,

Thanks for that very interesting post on UTube. It has often occurred to me too that my MPN has been present for a lot longer than when I was diagnosed c five years ago but I certainly didn’t suspect it could possibly trace back to birth!😳

You also posted recently that you suspected you might have PH and I think Hunter mentioned in his reply that you can have a test to establish whether this is the case. Maybe you’re just suffering a bit of exhaustion due to your very challenging physical regime!?

Sorry to hear your mother isn’t so well. I hope she will improve very soon.

Keep sending the posts! The more information we have the better armed we are to cope with our MPNs!

Ettiel

[socrates_8 in reply to Ettiel]

Thank you Ettiel...

My mother is doing fine too...

I am booked in for a transthoracic echocardiogram to try to determine my pulmonary pressures etc...

Hopefully, I shall learn more soon. I fear that it is more likely one of the many adverse side-effects that comes w/ having to take such toxic medications...

However, and without said medications, I might not be here at all...?

Take cafe Ettiel...

Best wishes to you & yours for a happy festive season also...

Stay safe & well...

Steve