Suffered for ten years. Factor V Leiden discovery put me on Coumadin in lieu of colon resection, but attacks continued. Heart attack added Plavix and 81mg aspirin to meds, but attacks continued. ET diagnosis put me on hydroxycarbamide. Platelets came down, and no more attacks for the last year and a half, thank God. Anybody else experience Messenteric Ischemia before MPN diagnosis?