My husband has got pv jak2 positive. He has an enlarged spleen. Over the last 4 weeks he has got a permanent dull ache in his left side. Recently his gp called him in as his liver function test has shown his gamma gt levels are constantly rising he queried alcoholic!!!. My husband only has a couple of drinks on a weekend nothing heavy at all.i asked the gp could it be the asprin that's causing his levels to be high he said no. We are so confused as we've read up about asprin and it can change the enzymes in the liver. Does anyone know if there's anything you can take to ease discomfort for the spleen?