Recently posted a question re alternative entry sites for venesections but after discussing this with my consultant, he's now prescribed Hydroxy as the alternative. My veins were hardening due to the regular blood letting-just having a simple blood test on Monday last week proved trying for the bleeder (& me!). Sooooo, the Hydroxy it is (chickened out the first time I was prescribed it) but how can an oral chemotherapy drug which is recommended you don't even touch with your fingers be safe to ingest?!!! I'm feeling very wobbly about taking it with all the potential horrible side effects so I guess what I'm looking for are some reassuring posts from you guys as to the positives. I also think it's the reality that's kicked in that my condition (PV/ET-JAK 2 +) may be moving on & I need now to come out of the warm waters of that lovely river in Egypt - de nial! Anyone in a similar situation in Dorset or who has just started with Hydroxy?