I was diagnosed with wet MD in my right eye in February this year at age 48. The first six Lucentis injections were pain free, if ineffective. The legion in my right eye is described by my consultant as being 'very aggressive' and continues to leak. I had a course of PDT, also to no avail, and then back to the Lucentis. Injection seven hurt a bit, and left my eye *very* bloodshot for a week (it looked like someone had poured red paint into it) but injection eight, a couple of weeks back, was the stuff of nightmares. I had told the consultant about the pain the previous time, and he said it happens every now and then but didn't seem too concerned. Injection eight felt like I had no anaesthetic at all, it hurt like Hell - just as you would imagine if you had no anaesthetic (I did, the usual amount in fact). I also couldn't see anything after for some while, and ended up with large air bubbles in the eye for a few days.
But it was the pain that troubled me most, to the point where I am seriously considering whether I want another injection in two weeks time. Has anyone else experienced severe pain during a Lucentis injection? Does the fact that the needle goes into the same place every time make a difference, in that it could have sensitised the eye to the injection?