Investigating gut health in SLE - findings from a LUPUS UK funded study

[Debbie_kinsey]

A recent study, funded by LUPUS UK, found that people with SLE may have a "leaky gut", also called "higher gut permeability". The researchers plan to do further work investigating gut health and SLE to see if this would lead to new ways to help people with lupus. You can read about their findings here: lupusuk.org.uk/investigatin...

[Star13]

SIBO is also very common which again is an over growth of gut bacteria and is seen a lot in the guts of people with MCTD and UCDT according to my Gastro.

[Cwmtaf]

Thankyou Debbie. This is really interesting.

[BeeManShrop]

Thanks Debbie That is a really interesting piece of research and the results of a wider study will hopefully lead to other new SLE treatments. There has also been some useful dialog here recently about lupus and gastritis -- makes me wonder whether there is a link here?

On another theme we never seem to discuss whether there is a link between SLE patients and their appetites. My wife since being diagnosed with lupus, following a really bad flare, has only a very poor appetite. She is normally quite happy with a meal that would not satisfy a small child. Again just wondering whether there may be a link to the gut here too. Thanks again.

[sarahalice]

Thank you for this !I did the zoe study where they test your fat and sugar response, as well as your gut bacteria. I was happy to discover my fat response was normal and sugar is excellent. However my gut tests were not as positive. I have good ratio between my good and bad gut bacteria, but I have very poor gut diversity. The trouble is, though I can (and hopefully I have) improved this with a better diet, every day I take my meds, they destroy and disrupt my gut flora. So leaky gut might trigger SLE, but the meds they give us for lupus do not help to mend a leaky gut and actually make this matter worse.

I cannot wait for more research in this area.

X

[Turquoise-1]

Hi Debbie_kinsey

Thanks for sharing this which, for me is very relevant, helpful & interesting.

It backs up what I’ve recently been told by both Consultant Gastroenterologist & also GI Physiologist that Lupus can & does affect the gut. My tests/treatments and symptoms continue….

All the best 🌸