I'm in my 3rd week of methotrexate with, thankfully so far, no noticeable side effects. I am, however, decreasing my prednisolone by 2.5mg every 2 weeks (and increasing MTX by 2.5mg every 2 weeks, different week/day) which means that my symptoms are getting worse - it's all still early days for me. My rheumatologist prescribed folic acid to be taken the day after methotrexate but my doctor is now saying to take folic acid every day to see if that helps. I asked if I needed to take a day off on methotrexate day and she said no.
Obviously I'm no expert but I thought the reason for taking folic acid on a different day was because the methotrexate doesn't work as well if you take them together? So do I take it every day? Just the day after? Or some other combination? I've just spoken to the 'specialist nurse' and she seemed to know even less than I do, which is pretty good going as I know precious little!