I have been treated with 6 monthly rituximab infusions now for two years with good results , now became of a backlog in rheumatology im 2 months overdue. I am now having a return in symptoms , fatigue, muscle aches, joint pain ,lymph node swelling, increased dryness generally , difficulty sleeping and palpitations with sternum pain . I didn’t realise that palpitations can be a symptom of Sjögrens, i was started on bisoprolol a few years prior to my actual diagnosis of Sjögrens. I was wondering if anyone else has had the same problems after a delay in scheduled treatment. I have been given 1st of march as a possible date for next infusion. I haven’t been to the gp about the symptoms, I don’t know if they will do much, other than tell me to wait until March. Has anyone any advice ?