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Methotrexate and pregnancy

Hi all I just need a bit of advice from someone who has experienced the above. I’ve been taking methotrexate for over a year now but I’m the past 6 weeks have only had it twice due to having the nova virus. Last week I found out im pregnant but I’ve been told by my dr and specialist that a termination would be best for all. This really isn’t sitting well with me and I feel Swedish for being more careful to start with but I guess what I really want to know is if anyone who like myself took methotrexate in the early stages went on to have a healthy baby? I’ve been told there might be a good chance my baby won’t develope correctly meaning there quality of life is in question. I don’t want to be selfish but I also don’t want to just give up. Any advice at all??

3 Replies

Oh I really feel for you. I was taken off methotrexate and told it had to be out of my system for a year before trying to conceive. It was 17 years ago but recently started methotrexate again and again I was told I wasn't to get pregnant whilst taking it. I wish I could give you better news.



I found this abstract


Much depends on the MTX dose taken I think and how pregnant you are.

You really need someone knowledgable to go through all the evidence with you and then it's up to you to decide on the risk V benefit. Have you been referred to a Gynaecologist?


Thank you both for your advice the link you supplied is very positive and something I will discuss with my partner. I'm booked in on Thursday with the gyno so fingers crossed all will be well


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