Methotrexate

[lilly60]

What time of day is best to take Methotrexate just been prescribed 2.5 taken 4 times weekly

Thank you

[PMRpro]

That is a very unusual way to take mtx - it is usually once weekly on a specified day. I would check with your doctor.

[Sjanec]

I agree usually you have weekly dose on a set day each week and I take folic acid tablets on the days I do not take my Methotrexate I would check prior to taking these

[Ianrussell69]

Hi it’s normally once a week ? I was taking mine 5/6 at night on a Friday then @ duvet day sat when taking tabs but had very little side effects with the injections

[HazelW]

I agree with the other comments on here - once a week on the same day every week & folic acid on other days. Would definitely check this out. Hope it helps you - it has been a godsend to me.

[wallock]

I take 20mg a week and split it 50/50 on consecutive days as it upsets my digestive system too much otherwise. The Lupus clinic is fine with that although it is normally once a week. DOn’t forget to take folic acid on the days you don’t take Methotrexate. I only take it three times a week as I read that it can make the Methotrexate less effective.

[Jhpc]

I take 3 x 2.5 methotrexate tablets once a week on a Sunday then take 2 folic acid tablets every Thursday.

[lilly60]

Hi thank you all

Checked with my doctor he still says 1 x 2.5 tablet four times weekly and folic acid on days I don't take it

He explained that because it's a high dose it is better split up

After blood tests every 2 weeks they will look at either changing the strength or frequency x

[VonnieD]

I've just been prescribed methotrexate for Polymyositis and been advised to take it in the morning after breakfast, I hope that helps.

[lilly60 in reply to VonnieD]

It does help thank you

VonnieD

[Joy_1]

Yes do double check when you need to take your MTX as others have suggested.

I take mine once a week. Through trial and error I have found taking mine just before I go to bed is the best time to take it. That way I sleep through the worst of it and have more or less fully recovered by lunchtime the next day.

[Dalilatm]

Hi!

Same here. I had it just once a week and folid acid everyday. It used to cause me so much dizziness so I'd have it after dinner and rest at home after. Hope it all goes well!

[Niccigrace]

I take 7 X 2.5 mg tablets every Monday and Folic acid on a Friday. Never tried taking it at night I will have to try it.

[Poshcards]

Is definitely a once weekly dose! Mine is Wednesday night before bed, then the nausea isn’t so bad xx

[farmerfeste]

Check with reumatoligist gp,s can and do some very silly things even with serious dope like you take

[lilly60 in reply to farmerfeste]

Checked with my Rheumatoid specialist it is correct it is so that it does not upset my stomach too much I have a lot going on I think they are thinking of me...................... Hopefully

[farmerfeste]

It's is common for patients who react this way to be offered thier methotrexate by injection

when I started I was sternly warned that it could only be taken on one day per week after

about te years later it was decided it was doing no good and stopped then I stopped having uti,s finger nail infections healed up and I started to feel a bit better not a drug to mess about with