Hi all I don't know if it's the 5mg weekly dose of methotrexate or the omega 3 liquid ive bern taking but touch wood fingers crossed I've been taking both for the past 2 months and I feel like a new person. I have no fatigue, pains apart from slightly swollen joints in my fingers in the morning but I feel the best I've felt for a long time and I pray it continues. If anyone is interested ive been taking a teaspoon of lionheart omega 3 which is made by bare biology,! Whatever it is it could be the medication and the omega 3 but I'm going to continue!