this link will bring out a lot of smiles:
umassmed.edu/news/news-arch...
Here is a summary:
Long Noncoding RNA Found to Quell Inflammation
JULY 7, 2016 A long noncoding RNA (lincRNA)βcalled lincRNA-EPSβresponsible for regulating innate immunity has been identified by a team of scientists at UMass Medical School. The findings were published in Cell. Katherine A. Fitzgerald, PhD, professor of medicine, is senior author on the study.
Abundantly found in macrophages, lincRNA-EPS keeps the genes that trigger inflammation turned off until a pathogen is encountered. This discovery points to an unrecognized role for lincRNAs in the immune system and may lead to new insights into inflammatory diseases caused by uncontrolled immune responses such as lupus or inflammatory bowel disease.
βThese findings suggest that there is an unexplored layer of regulation controlling inflammatory and immune responses,β said Dr. Fitzgerald. βWeβve demonstrated an important functional role of a lincRNA in the immune system.β