Anti Ds DNA antibodies confirmatory for Lupus?

Hi all...received a copy letter from Guys hospital about my recent blood tests... And it's the anti dsDNA bloods that have shown mildly positive so he's repeating them.... Am i correct that these antibodies are the ones that you wouldn't tend to put down to anything else and I can almost be certain I have lupus (considering my history too)? This tiredness is getting worse...or more noticeable.... Why do they wait 3months to see me again?....

5 Replies

  • I am having lupus but my ds DNA is negative since diagnosed. .

  • Hi jp83,

    You are correct that anti dsDNA antibodies are highly specific to lupus and their presence is the hallmark of the condition. They are rarely found in other conditions.

    They may be wanting to repeat the tests because they are only mildly positive. A strongly positive result would provide almost total proof of a diagnosis. The level of these antibodies can be used as a rough measure for disease activity, so repeating the test after a few months will give them a better idea of how active the lupus is.

    Would you like some more information about lupus and how it is diagnosed? I would be happy to send you one of our free info packs. Just send me a private message or email with your name and address.

  • Hi Paul I received a pack recently from you already, it's very helpful thank you. Thanks for responding, I am so tired I wish I could get something to help with it sooner rather than later.

  • Hi Jp83

    Have you been tested for anaemia and thyroid ?. These can cause excessive tiredness and be successfully treated. Your GP can do this. X

  • Hi yes I'm on thyroxine for hypothyroidism anyway and they run all bloods as part of the these are normal.

    Thank you x

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