LUPUS UK
20,869 members16,565 posts

Anti Ds DNA antibodies confirmatory for Lupus?

Hi all...received a copy letter from Guys hospital about my recent blood tests... And it's the anti dsDNA bloods that have shown mildly positive so he's repeating them.... Am i correct that these antibodies are the ones that you wouldn't tend to put down to anything else and I can almost be certain I have lupus (considering my history too)? This tiredness is getting worse...or more noticeable.... Why do they wait 3months to see me again?....

5 Replies
oldestnewest

I am having lupus but my ds DNA is negative since diagnosed. .

Reply

Hi jp83,

You are correct that anti dsDNA antibodies are highly specific to lupus and their presence is the hallmark of the condition. They are rarely found in other conditions.

They may be wanting to repeat the tests because they are only mildly positive. A strongly positive result would provide almost total proof of a diagnosis. The level of these antibodies can be used as a rough measure for disease activity, so repeating the test after a few months will give them a better idea of how active the lupus is.

Would you like some more information about lupus and how it is diagnosed? I would be happy to send you one of our free info packs. Just send me a private message or email paul@lupusuk.org.uk with your name and address.

2 likes
Reply

Hi Paul I received a pack recently from you already, it's very helpful thank you. Thanks for responding, I am so tired I wish I could get something to help with it sooner rather than later.

Reply

Hi Jp83

Have you been tested for anaemia and thyroid ?. These can cause excessive tiredness and be successfully treated. Your GP can do this. X

Reply

Hi yes I'm on thyroxine for hypothyroidism anyway and they run all bloods as part of the tests...so these are normal.

Thank you x

Reply

You may also like...