appear polytypic. AE1/AE3 is negative. The lymph node shows prominent sinus histiocytosis. Features are consistent with a reactive hilar lymph node. In summary, there is a prominent non-specific bronchial inflammatory infiltrate with no obvious evidence of lymphoid neoplasia.
Tumour was set for further investigations.
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Written by
AnnaDora
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I hope you have recovered well from your lobectomy.
Polytypic means different forms.
AE1 and AE3 negative show that the cells do not make Cytokeratins (which are sometimes present as a positive marker in cancer cells)
Prominent Sinus Histiocystosis is a rare benign disease of unknown cause and can present as lymph node enlargement, you report states that this is due to reactive hilar lymph node, which means the lymph nodes have enlarged due to fighting of an infection.
In summary as stated there has been some bronchial inflammation with no evidence of present of cancer (lymphoid neoplasia) which is very encouraging.
Your lung cancer nurse specialist may perhaps clarify the tumour is set for further investigations, which may mean the routine follow up 3 monthly CT scans, but would be good to check that is what they have meant by this.
I hope this all makes sense Anna and if you would like to discuss anything you can email ask the nurse at lungcancerhelp@roycastle.org or call our free phone nurse led helpline on 0800 358 7200 Monday to Thursday 0900-1700 and Friday 0900-1600.
Hi AnnaDora, as you have found these letters written by pathologist (and similar by radiographers/radiologists) are not intended to be understood by patients or lay people! They may as well be in hieroglyphics!
I read that whatever they were looking at is 'negative' which is good (positive would have meant they'd found something of interest).
All their terminology suggests findings show inflammation likely by infection which prompted further investigation presumably as a follow on from imaging. did one of the hilar lymph nodes light up? (did you have a PET scan?).
With no evidence of neoplasia which can be abnormal tissue that could be suspicious, it reads to me that this is reassuring.
Always discuss your results with your consultant who can be more specific and explain what this means to you..... good luck with your continued recovery.
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