Hello: a few weeks ago my partner was diagnosed with ITP (never had a bone marrow biopsy) and was put on 80mgs per day of prednisone. After one week his number went from 25 to 79 but the second week on the same dose they dropped to 27. Has anyone have this happen? We expected it to keep climbing or hold steady but not drop again until at least after the steroids were discontinued. Also, is it normal not to have a bone marrow test to confirm the itp and that it isnt something worse? Thank you so much for your time.