Husband has itp. 2 months , 3 different treatments, 4 day super dose of steroids, failed. Globulin treatment one week , got up to 60000 platlets, stopped treatment , platlets crashed , now doing 4th treatment of a 4 week treatment of Rituxin... everywhere drops below 10000.. last week had a change in white cells and platlets did not drop over weekend, but by this Friday crashed to 5000. Doing last rituxin , just for the hell of it , I guess. Spleenectamy is next. Not feeling like we have tried enough. Anyone have any suggestions. I am currently waiting on a call from his Dr so I can ask more questions. We have not been looking elsewhere for answers for this because Dr seemed so positive about each treatment. Now I am feeling strung along.