I just wanted to ask has anyone else got Hughes S. and suddenly got lowered platelets? I,ve got this now, and the g.p. says they will just do odd blood tests to see how it goes. Well thats o.k. but I want to have some dental treatment, and as I,m on warfarin(20years), what should I do, will it right itself? I lightly knocked my hand 3 days ago, and that has still got a fair size bruise,so how have others coped.? I don,t do things by halves, having already got an enlarged heart that beats irregularly, so it,s a bit of a worry. Many thanks.top_hole.