Hi, my specialist at Princesa (Madrid) says the same about reducing the target as apparently they have done some recent research here (paper pending I believe) that demonstrates in general no major benefit going over 3 with warfarin. I'm not on asprin as well but made the switch from sintrom to warfarin last year.
In general I have found my team here far more cautious on everything compared to the UK.... who is your consultant at La Paz? Will ask another APSer who goes there what she has been told recently. Personally I have kept to making sure I am closer to 3 but don't need the closer to 4 that I needed on sintrom.
Im on aspirin and warfrin my inr has to be between 2.5 to 3.5. Most of the time it is around 4. Only been on the aspirin three weeks and since then i feel alot worse. But did have three trips to A and E over easter weekend before they took my symptoms seriosly!
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