INR Crazy times!

[Greenmil3]

Go figure! Last week at 4.7 little higher than I need so as I self medicate and adjust dropped from 8mg 7mg alternate nights to 7mg for 7 days and arrive at 1.8 tonight!! No diet changes no increase in anything so so frustrating. The only change is a change in pain med from 15/500 to 30/500 codeine but can that cause this?

[HollyHeski Administrator]

Dont know about codeine but have you got dome heparin while your INR is so low?

[Greenmil3 in reply to HollyHeski]

No just going to hit the warfarin button large for a couple of days usually does the trick!

[HollyHeski Administrator in reply to Greenmil3]

You know your body 👍x

[KellyInTexas Administrator]

Too many nights in a row of 7 mg.

Some hematologists like to see what a weekly average of mg total is, as well as day to day, what will hit through in 48 hours.

When you look accumulated 7 mg for 7 knights in a row- that totals too much mg loss.

I’ve also learned to do 1/2 and 1/4 doses.

You might try 7.25

7.5

Are you bridging with clexane for a few days until it comes back into range?

[KellyInTexas Administrator in reply to KellyInTexas]

Sorry Greenmil- I’m just seeing that you said you you did alternate the nights that you lowered the mg, not 7 nights in a row.

It still must have been too much of an accumulated drop in mg.

( sorry, I’m in a migraine today, I apologize. I had a rituximab infusion a week ago today, and an infusion lowers my antibodies- so I have noticed I have to lower my mg on warfarin also. It’s the warfarin roulette for me also right now. I had to inject over lunch. I find it very helpful! )

However, with my already poor vision, add a low inr and my ability to read is diminished. Sentence quiver and warble.

[Greenmil3 in reply to KellyInTexas]

Kelly that is no problem with your writing and am feeling for you in your roulette struggle get better soon xxx

[dottiedoris]

I find that, when I hit 4.7, then I just take 2 or 3 for one night (or 5’s for 2 nights) and I’m back in range (3.5). If I’ve ever needed to stop warfarin for surgery, I’ve usually dropped down to 1 within 2 days so mine does drop pretty quickly but yours may take a little longer. My INR is always affected if I change any of my other meds or I’m in pain.