Inr crashed : My target inr is 4 Today... - Hughes Syndrome A...

Hughes Syndrome APS Forum

10,413 members10,622 posts

Inr crashed

Tim_Thorpe profile image
5 Replies

My target inr is 4

Today self tested inr was 2 😐 take fragmine injections when inr is around 3 or below

Felt unwell the last couple of days as recently prof hunt has raised my azathoiprine dose from 150 mg to 200mg. Daily . Apart from it crashing my inr think it’s making me feel really ill 😐

Thinking about stop taking it ?

On the good side in the past when my inr falls to 3 or below I would always get amourus fugax a type of Tia which I think is a good thing any thoughts why I don’t seem to get amourus fugax any more even with such a low inr of 2 ??

Written by
Tim_Thorpe profile image
Tim_Thorpe
To view profiles and participate in discussions please or .
Read more about...
5 Replies
HollyHeski profile image
HollyHeskiAdministrator

Its possible that the azathioprine can be thinning the blood, as I've looked at side effects and one is bleeding. Taking it wouldn't show with the INR.

There's quite a list of possible side effects, so yes it could be making you feel rough. It may be just your body getting used to it, esp. the higher dose. I wouldn't just stop without getting medical advice.

I would put a call through to Prof Hunt and report how your feeling. (Pm me if you need the number)?

Hope it all improves soon xx

Tim_Thorpe profile image
Tim_Thorpe in reply toHollyHeski

Thank you 👍yes the number would be great

MaryF profile image
MaryFAdministrator in reply toTim_Thorpe

I hope it all settles down for you, it may take a while, and so much virus around currently, it is sometimes hard to find where one thing ends and another begins. Keep well. MaryF

lupus-support1 profile image
lupus-support1Administrator

Tim, I can understand your concerns and feeling so unwell, but please do not stop the AZA without referring to your specialist.

I am so sorry you are having such a terrible time.

With good wishes,

Ros

WendyWoo50 profile image
WendyWoo50

I'm sorry u r feeling so ill but in my opinion it is more likely u feel ill due to a low INR rather than the Azathioprine.

It is well known that Azathioprine inhibits Warfarin (and so more is required) I crashed to 1.1 when I started Azathioprine and now take 18-20mg of warfarin (the dose isn't important - the INR is !)

See how u feel once the INR is back at 4.

When my INR drops much below 4 I feel achey all over - flu like, have terrible headaches, pains in muscles particularly my legs. (Which I assume is due to the blood being stickier and not carrying enough oxygen around my body). I also get what I think r micro clots in my head, which are very painful and stop me in my tracks!

As I said b4 Azathioprine is correctly dosed according to weight so that each person on it has the same amount in their bloodstream. For example: My father is on 150mg and I'm on 200mg. He is thinner than me and weighs less.

So I wouldn't get hung up on the dose u r on because it will be right for ur weight and should be adjusted if u gain or loose weight.

So give it a chance and see how u feel when ur INR is up again! Good luck 💋

Not what you're looking for?

You may also like...

Inr crashed

Went back to work wensday . Self tested thursday 2.9 have to take fragmine injection if below 3 ....
Tim_Thorpe profile image

Inr crashed

Went to st Thomas today for a venus blood test to compare it with my self test machine which was...
Tim_Thorpe profile image

Tooth extracted

Just had tooth taken out today 🙂 My dentist wouldn't take tooth out as I'm on wafrin target of Inr...
Tim_Thorpe profile image

Inr still not going up 😐

Should I take injection tonight ? Called on call register at st Thomas last night wasn't a very...
Tim_Thorpe profile image

Inr crashed

Took inr this morning 2.6 so take fragmine when below 3 my target is 4 Emailed Anticoagulation...
Tim_Thorpe profile image

Moderation team

See all
KellyInTexas profile image
KellyInTexasAdministrator
MaryF profile image
MaryFAdministrator
HollyHeski profile image
HollyHeskiAdministrator

Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them.

Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked.