Hello. I happened upon this site because my 19 year old was diagnosed with APS and a genetic blood mutation when he was 16. It's been such a relief just to read about other people's experiences. My son was originally on warfarin and then after about 9 months, we tried Xeralto so we could avoid the monthly testing. 3 weeks after switching, my son had a couple of seizures 2 days in a row. We switched him back to warfarin and baby aspirin was added too. Lots of tests were done- we're in Los Angeles and being managed at Children's Hospital. It ends up through neurological testing, EEG, his brain showed epileptic spikes. He was a perfectly healthy kid before all of this (other than the APS). Whether Xeralto caused this, I don't know. He's been seizure free since switching back to warfarin. His hematologist hadn't heard of Xeralto causing seizures but wondering if anyone else has heard of this problem. There was no bleeding- I know there's been lots of lawsuits for Xeralto and excessive bleeding. He's doing well now.