I'm new to this blog, the reason why I looked up my blood disorders is that I am feeling lately extremely tired and my INR is being checked twice a week in the hospital. It is either too high or too low. Yesterday the hospital called and it was 6.9 and on Friday it was 1.7. My range should be 3 to 3.5. Very annoying to have to drive to hospital. They think it is stress......husband quintuple bypass last year and both our sons live abroad! Is anyone out there having similar symptoms and as anyone the same blood disorder combination? Lupus inhibitor.....Leiden V factor and S.Def? Would be very grateful for any information.