Six mos. ago I was post five IVF failures and had selected an egg donor, and was ready to start my family. I never miscarried but just had no implantation. But then I fell, broke my ankle and was in the ER ten days later with dvt in 3 veins of my left leg. I was put on coumadin and just got off two weeks ago. They did a hyper coagulation panel and found now that I have APS. I am in shock and am scared. I know the dvt is resolved b/c my ultrasound was clear, but I am now to see a hematologist and determine if I must go on blood thinners for life. I am almost 43, and am heavier than I should be. I have interstitial cystitis (also auto immune) but never anticipated this was not just some fluke thing. My left leg still hurts from the resolved clot...it throbs and my ankle is quite painful still despite the break being healed. I feel like this is all just some nightmare. Our egg bank will not likely let me continue with their guaranty program ( they promise a live birth if you pay a higher fee) and now my whole life is turned upside down. I have an identical twin who has none of these issues...what the heck happened in my case? So weird. I hate coumadin...it gave me terrible headaches every day...and my INR was all over the place every week. I had a high dose...10 mg every day. Is it possible the blood test was wrong? If I had a dvt that came with a broken ankle and wasn't spontaneous , does that mean I must take warfarin for life??? I am devastated and seeing the damage this diagnosis can cause is just so scary. I am also hypo thyroid and losing weight is so incredibly tough...it was darn near impossible before I was injured and now is even tougher. If there is anyone in Massachusetts USA that can help with a recommendation for a good specialist, I would welcome it...also just to share info. I am just so confused at how this has happened.