Does anyone get these related to Hughes Syndrome? My Rheumatologist has noted them twice and my GP has now taken 3 in a short time - all abnormal - she worried that my liver won't metabolise the warfarin properly, I am worried I might have clots in the blood supply to the liver or something! Anyone had anything similar? I don't know the ranges of the most recent tests but as the GP rang me at home to tell me to come in for another I guess they must be pretty abnormal. My INR has just jumped from 2.4 to 3.9 (highest is has ever been - but I have had a nasty cold virus and not been eating very well) so I suppose that might have had an impact on my liver?